A substance that is broken down (metabolized) from serotonin. A high level of 5-HIAA in a 24-hour urine test sample can be used to confirm whether a person’s symptoms, such as flushing of the skin (particularly the face) and diarrhea, are due to carcinoid syndrome. 5-HIAA also can be done by blood known as the 5-HIAA Serum.
A substance that can be found in the blood or in the body that is associated with the presence of disease. In cancers, specific biomarkers can point to the presence of specific cancers. With names like CA 125 (which can indicate ovarian cancer) and CEA (which can mean lung, ovarian, breast, pancreatic, or digestive tract tumors), biomarkers are also called tumor markers. Some biomarkers related to carcinoid tumors are CgA and Ki-67
An imaging test that uses a very small amount of radioactive dye to help diagnose problems in the bones. It involves an injection with a radioactive substance called a radionuclide. A bone scan may also be called bone scintigraphy, a radionuclide scan, or a nuclear medicine scan.
NETs that develop in the lungs. There are two types depending on where they occur. Central bronchial NETs are located in trachea (windpipe) and around the main central area of the lungs. Peripheral bronchial NETs are in the outer areas of the lungs. Bronchial NETs are the second most common cause of carcinoid syndrome. Bronchial NETs may also be referred to as bronchial carcinoids or bronchial carcinoid tumors.